Richard Axel

Richard Axel Columbia University
Professor, HHMI Investigator
Homepage
MD , Johns Hopkins University School of Medicine (1970)
Publications

Compare

vs.

Research Summary

Richard Axel's laboratory is interested in the representation of olfactory information in the brain and the neural mechanisms that translate these representations into appropriate innate and learned behavioral responses. A randomly distributed population of sensory neurons in the olfactory epithelium is consolidated into a discrete stereotyped map of neural activity in the olfactory bulb. Stereotyped projections from the olfactory bulb to the cortical amygdala mediate innate aversive and appetitive behavioral responses to odors. Distributed, unstructured projections to the piriform cortex implicate this cortical structure as a mediator of learned olfactory behavior. Random input to pyramidal neurons of the cortex allows the organism to contextualize a rich diversity of novel sensory experiences, a feature consistent with the role of this brain center in mediating learned olfactory associations and behavior. Our studies reveal that the anatomic organization and functional logic of olfactory circuits in Drosophila is remarkably similar to the olfactory system of mammals, despite the 600 million years of evolution that separate the two organisms.

Similar Researchers

Harvard University
Cambridge, Massachusetts
Profile
Publications
Percentiles
Citations
76th
Papers
11th
Funding
66th
Olfaction, Neuroscience, Synapses & Circuits, Mouse Biology, Signal Transduction . . .
Rockefeller University
New York, New York
Profile
Publications
Percentiles
Citations
63rd
Papers
39th
Funding
87th
Olfaction, Neuroscience, Drosophila, Receptors, Genomics & Genetics . . .
Mount Sinai
New York, New York
Profile
Publications
Percentiles
Citations
45th
Papers
26th
Funding
57th
Genomics & Genetics, Olfaction, Nucleic Acids, Neuroscience, Mouse Biology . . .
Columbia University
New York, New York
Profile
Publications
Percentiles
Citations
47th
Papers
50th
Funding
68th
Olfaction, Neuroscience, Receptors, Genomics & Genetics, Mouse Biology . . .
Stanford University
Palo Alto, California
Profile
Publications
Percentiles
Citations
77th
Papers
71st
Funding
94th
Neuroscience, Drosophila, Olfaction, Synapses & Circuits, Genomics & Genetics . . .

Percentiles

Citations*
91st
Papers*
70th
Funding
81st
Efficiency
Coming Soon

Normalized Percentiles

Citations*
78th
Papers*
39th
Funding
74th
Efficiency
Coming Soon

Funding by Source
2008-2016

-
*Cited papers in our current database **Coming soon